An Indian American Scientist Devises Blood Test to Detect TB

There is good news in the waiting for all that were hoping science would find something for early detection of active tuberculosis (TB). Well, the answer’s out, and an Indian American is at the front of making it happen.


Known as the ‘Khatri test’ christened after Dr. Purvesh Khatri of Stanford, he and his team of American researchers have developed a  effortless blood test that can precisely diagnose active tuberculosis (TB) – a disease that hits 9.6 million people each year and kills 1.5 million worldwide.

The research team has uncovered a gene expression that differentiates patients with active TB from those with either dormant TB or other diseases. Elaborating on the effectiveness of this new-found solution, Purvesh Khatri, assistant professor at the university was quoted as “The test can be used not only for diagnosis and to inform treatment, but also to study the effectiveness of different treatments. The test’s hugely accurate negative response would be especially helpful in monitoring the effectiveness of treatments during clinical trials.”

The test operates on an ordinary blood sample and discards the need to collect sputum – a common test for TB. Furthermore, the test results also indicated that the test could also detect a TB infection even if the individual also is infected with human immunodeficiency virus (HIV).

The success rate of the test working right is that it is 86 percent sensitive in children it works in adults as well.

The researchers also explained that if the test comes up negative, it’s right 99 percent of the time.  The basis being that, of 100 patients who test negative with the Khatri test, 99 do not have active TB.

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